Straumann Dominik

Group Leader

PD Dr. med. D. Straumann

 

Name of the Institution

Clinical Vestibulo-Oculomotor Laboratory
Neurology Department
Zurich University Hospital

Street

Frauenklinikstrasse 26

City

CH-8091 Zürich

Phone

+41-44-255 55 00

E-mail

Group Members

Sarah Marti, M.D. (postdoc)
Antonella Palla, M.D. (postdoc)
Konrad Weber, M.D. (postdoc)
Tanja Schmückle, orthoptist
Elisabeth Schafflützel, orthoptist
Albert Züger, engineer
Theresa Schneider, medical student (dissertation)
Bruno Marques, medical student (dissertation)
Stephan Bosshard, medical student (dissertation)

Main Field(s) of Research, Abstract

The long-term goal of this research is to better understand central and peripheral diseases of the ocular motor system in humans and to assess potential treatments. The focus of interest is on the three-dimensional (horizontal, vertical, torsional) kinematical properties of ocular rotations. Specifically, we explore eye movements in patients with (1) strabismus, (2) cerebellar disorders, and (3) peripheral vestibular hypofunction to categorize and understand the three-dimensional (3D) kinematical aberrations of the eyes caused by peripheral or central ocular motor damage or impaired vestibular sensory input.

Main Fields of Research, Keywords

eye movement disorders; humans; neuro-ophthalmology; neuro-otology; neurology; three-dimensional ocular rotations; ocular kinematics

Special Techniques and Equipment

This research uses the latest techniques for evoking (motorized multi-axes turntable, linear sled, laser projection system), measuring (dual search coil technique, 3D video-oculography), and analyzing (rotation vector algebra, computer simulations) 3D eye rotations.

Education and Training

We have training opportunities for postdoctoral fellows (preferably with intended careers in neurology) and candidates of the Postgraduate Course of Medicine at the University of Zurich interested in the research topics mentioned above.

Selected Publications

Straumann D, Zee DS, Solomon D (2000) Three-dimensional kinematics of ocular drift in humans with cerebellar atrophy. J Neurophysiol, 83:1125-1140

Kori AA, Schmid-Priscoveanu A, Straumann D (2001) Vertical divergence and counterroll eye movements evoked by whole-body position steps about the roll axis of the head in humans. J Neurophysiol 85: 671-678

Bergamin O, Zee DS, Roberts DC, Landau K, Lasker AG, Straumann D (2001) Three-dimensional Hess screen test with binocular dual search coils in a three-field magnetic system. Invest Ophthalmol Vis Res 42: 660-667

Bergamin O, Straumann D (2001) Three-dimensional binocular kinematics of torsional vestibular nystagmus during convergence on head-fixed targets in humans. J Neurophysiol 86: 113-122

Schmid-Priscoveanu A, Böhmer A, Obzina H, Straumann D (2001) Caloric and search-coil head impulse testing in patients after vestibular neuritis. J Ass Res Otolaryngol 2: 72-78

Bergamin O, Bizzarri S, Straumann D (2002) Ocular torsion during voluntary blinks in humans. Invest Ophthalmol Vis Sci: 3438-3443

Marti S, Palla A, Straumann D (2002) Gravity-dependence of ocular drift in patients with cerebellar downbeat nystagmus. Ann Neurol 52: 712-721

Yakushin SB, Palla A, Haslwanter T, Bockisch CJ, Straumann D. (2003) Gravity-dependent adaptation of the human vertical angular vestibulo-ocular reflex. Exp Brain Res 152:137-142

Solomon D, Zee DS, Straumann D (2003) Torsional and horizontal vestibular ocular reflex adaptation: three-dimensional eye movement analysis. Exp Brain Res, 152:150-155

Straumann D, Steffen H, Landau K, Bergamin O, Mudgil AV, Walker MF,Guyton DL, Zee DS (2003) Primary position and Listing?s law in acquired and congenital trochlear nerve palsy. Invest Ophthalmol Vis Res 44:4282-4292.

Funding

Swiss National Science Foundation; Betty and David Koetser Foundation for Brain Research, Zurich, Switzerland.

URL

Link to "Forschungsdatenbank" of the University